PUBLICATIONs
221. “Machine learning prediction of patient-relevant toxicity to liposomal formulations via pre-dose metabolomics”
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M. Zhao, , Y. Wang, Y. Xiao, G. Hu, Y. Zou, J. Li, L. Zhao, X. Ye, H. Liu, João Conde*, Y. Zhao* C. Yin* and H. Meng*
220. “IL-10-accelerated cancer immunotherapy: Molecular circuitry, TME dynamics and translational implications”
...
Y. Tian, S. Fu, Z. Liu, X. Wang, Q. Wang, E. Shen, Q. Zhou, M. Ashrafizadeh, João Conde*, S. Wang* and Q. Yin*
219. “Preclinical validation of a therapeutic nose-to-brain delivery for gliomas using a mucoadhesive thermoresponsive lipid nanoparticle hydrogel”
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Leonardo D. Di Filippo, J.L. Duarte, Bárbara B. Mendes, Jhenifer Oliveira, Catarina F. Martins, Mariana F. Pereira, G.A. de Paula, T.C. Ribeiro, F.F. Haddad, I.D. Figueiredo, R.M. Sábio, B.S. Rosa, G. Morais-Silva, M. Thiele, C.C. Crestani, R.L. Nunes-de-Souza, E. Sasso-Cerri, M. Chorilli* and João Conde*
218. “Macrophage membrane-cloaked, ROS-triggered quercetin nanocarriers target ovarian lesions to treat polycystic ovary syndrome”
...
W. Li, Y. Guan, N. Song, F. Zhang, Z. Deng, T. Yin, Y. Yang*, João Conde*, W. Jin* and Z. Yin*
217. “On-demand biofilm shedding from dental implants via a rinse-triggered thermoresponsive coating in multiple in vivo mammalian and human models”
...
S. Ye, M. Zhang, Z. Wu, K. Zou, Q. Yu, R. Zhong, W. Huang, T. Yang*, João Conde*, W. Li* and L. Wang*
216. “Materials-guided gene-ionizable lipid nanoparticles to reverse iron-associated immune resistance in renal cancer”
...
X. Jin, Y. Hong, C. Yin, W. Guo, Y. Wang, R. Zeng, R. Liu, Z. Ding, X. Liu, S. Ren, Q. Liang, Y. Wang, X. Zhang, João Conde*, Y. Li*, X. Ma* and L. Gu*
215. “Measuring the composition and availability of human resources for health by sex in 204 countries, 1990–2023, and workforce gaps for universal health coverage”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
214. “Injectable thermoresponsive nanozyme hydrogel remodels the osteoarthritic microenvironment via synergistic ROS scavenging and chondroprotective repair”
...
K. Zhang, M. Jiang, G. Lai, M. Li, C. Lei, Q. Liao, Z. Wang, Y. Tian, T. Wang, S. Wu, C. Yang, Hu. Zhao, J. He, L. Lu, J. Meng, Z. Lin, X. Gan, Y. Liu, Z. Yuan, W.S. Toh, J.HP. Hui, X. Zheng, Z. Wang, M. Ashrafizadeh, João Conde*, Z. Bo*, Z. Wang*, S. Lu* and R. Wei*
213. “A bioadaptive proteostatic-metabolic signaling nanocircuit that dismantles tumor-stroma lipid symbiosis and reprograms the desmoplastic microenvironment in pancreatic cancer”
...
J. Zhu, C. Huang, X. Wang, J. Zhang, S. Fang, K. Zhao, Z. Yu, Y. Xu, M. Zhang, B. Gan, J. Lu, R. Zhou, Y. Chen, B. Zhang, X. Ren, J. Sun, João Conde* and S. Zheng*
212. “Intrinsically targeted endothelial EVs nanoplatform synergizes hydrogen sulfide for multi-target vascular repair”
...
B. Gao, J. Sun, P. Wei, Y. Zhang, Y. Tian, Y. Lin, M. Ashrafizadeh, D. Kang*, João Conde* and X. Niu*
211. “Global trends in maternal, neonatal infections and sepsis, 1990–2021: a systematic analysis”
...
X. Tan, Y. Feng, J. Hu, K. Sun, Y. Fu, Z. Zhang, M. Ashrafizadeh, João Conde*, A. Zhang*, D. Ma* and C. Duan*
210. “ZDHHC16-mediated S-palmitoylation of WDR4 enhances m7G modification and EGFR translation to facilitate liver cancer progression and lenvatinib resistance”
...
Y. Chen, Q. Dai, H. Wang, J. Zhang, B. Li, S. Li, Y. Tian, M. Ashrafizadeh, João Conde*, Z. You* and L. Jiang*
209. “Nanoparticle-mediated photothermal therapy for Acne vulgaris: recent clinical advances and AI integration”
...
P. Manivasagan, A. Joe, H-W. Han, T. Thambi, Y.J. Jeon, Y-R. Lim, J. Choi, João Conde* and E-S. Jang*
208. “Loss of mitochondrial SIRT3 links TCA cycle enzyme hyperacetylation to energetic decline in heart failure”
...
Y. Liao, X. Tan, G. Peng, Y. Ren, R. Liu, H. Liao, Z. Luo, Z. Cao, Y. Wu, M. Ashrafizadeh, João Conde*, C. Duan*, J. Hu* and R. Ma*
207. “Wearable near-infrared LED photothermal microneedle patches reduce periorbital wrinkles in a randomized pilot clinical trial”
...
Hyo-Won Han, D-H. Lee, A. Joe, Y.J. Jeon, Y-R. Lim, J. Choi, S.B. Lee, B-H. Bin, T. Thambi, João Conde*, P. Manivasagan* and E-S. Jang*
206. “Siglec-guided, dendritic-cell–tropic self-amplifying mRNA nanovaccine for TP53 neoantigens in pancreatic cancer”
...
C. Chen, Y. Wu, Z. Hou, F. Liang, C. Yin, J. Lin, P. You, S. Lin, Y. Zhang, Y. Zhou, H. Zhang, J. Kuang, H. Huang*, M. Pan*, João Conde* and Y. Pan*
205. “Advancements and challenges in CAR-NK cell therapy for cancer treatment”
...
Z. Xu, Y. Zhou, J. Kuang, Y. Li, C. Ye, H. Guo*, C. Yin*, João Conde*, S. Liu*
204. “Clinically relevant glycolytic reprogramming by ALDOA fuels immunosuppressive macrophages and pancreatic tumor growth”
...
J. Lin, M. Tian, Z. Hou, C. Chen, Y. Wu, F. Liang, L. Wu, P. You, Y. Mao, Z. Zhao, J. Kuang, X. Meng, Y. Zhou, W. Jia, H. Huang*, João Conde*, P. Zhao* and Y. Pan*
203. “Emerging global trend toward early-onset Parkinson’s disease across 953 global to subnational locations, 1980-2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
202. “BRPF1 is an epigenetic checkpoint for β-catenin and NF-κB to drive immune suppression”
...
Y. Hou, F. Ma, F. Meng, Z. Yang, Z. Wang, Y. Tian, ... , G. Sethi, D. Yin, R. Song, A.R. Aref, C. Nicot, M. Ashrafizadeh, João Conde*, J. Wang*, C. Zhang* and L. Liu*
201. “Global, Regional and National Distributions and Temporal Trends of Lung Cancer Burden Attributable to Residential Radon, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
200. “Spatiotemporal Distributions and Regional Disparities of Chronic Myeloid Leukemia in 953 Global to Subnational Locations, 1980–2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
199. “Mitochondrial DNA fragmentomics reveals specific cell-free mtDNA breakage sites as a novel biomarker for sepsis”
...
H. Liao, H. Huang, R. Ma, S. Hao, X. Zeng, R. Song, B. Chen, Z. Cao, W. Shen, X. Tan, Y. Tian, Z. Luo, J. Huang, M. Ashrafizadeh, João Conde*, L. Liu* and C. Duan*
198. “Mapping the burdens and inequalities of polycystic ovary syndrome in young female across 953 global to subnational locations, 1990-2040, with deep-learning-empowered forecasts”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
197. “Targeted membrane bionic supramolecular nanomaterials for overcoming CDK4/6 inhibitor resistance in breast cancer”
...
N. Xu, X. Li, T. Zhu, M. Ashrafizadeh, João Conde*, Z. Chi* and H. Wei*
196. “Advances in understanding the mechanisms of doxorubicin resistance in human cancers”
...
Z. Wang, H. Li, Y. Li, Y. Tian, G. Sethi, R.J. Reiter, M. Aschner, F. Hooshmand, N. Nabavi, João Conde, A.R. Aref, M. Ashrafizadeh*, W. Huang*, C. Nicot and Y. Wang*
195. “Folate-targeted Cu-based metal–organic framework nanoplatform for synergistic antihistamine, gene and chemodynamic therapy in hepatocellular carcinoma”
...
D. Ding, L. Wang, M. Ashrafizadeh, João Conde*, B. Yao* and Y. Yang*
194. “Deep learning forecasts reveal widening global inequalities in global-to-local childhood and adolescent cancer burden”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
193. “Integrative multi-omics analysis reveals gut microbiome-bile acid axis dysregulation driving NAFLD progression and identifies Faecalibacterium prausnitzii as a therapeutic modulator”
...
S. Zhu, M. Zou, Q. Wu, Z. Huang, Y. Zou, T. Tan, Y. You*, H. Luo*, João Conde* and X. Dong*
192. “Global to local burdens, inequalities, and achievable frontiers of child and adolescent malignant neoplasm of bone and articular cartilage across 953 countries and sublocations, 1990-2040”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
191. “A predictive rheological framework to define printability of thermo-sensitive bioinks using non-temperature-controlled bioprinters”
...
I. Anjos, T. Vieira, T. Aktar, J.C. Silva, Barbara B. Mendes, João Conde, L.F Bolaños, S. Fernandes, C. Leal, J.P. Borges and D. Limón*
190. “Smart multifunctional hydrogels with shape memory, conductivity, self-healing and adhesive properties for biomedical applications”
...
H. Huong, C.H. Luu, V.H. Giang Phan, G. Janarthanan, N-T. Huynh, H.T. Nguyen, N-Y. N. Ha, H.T. Ta, S. Vijayavenkataraman*, João Conde* and T. Thambi*
189. “Dexmedetomidine restores mitophagy and limits reperfusion injury to protect cold-stored organs”
...
X. Tan, Y. Liao, Y. Liu, G. Chen, G. Peng, B. Chen, S. Ren, Y. Liao, Y. Xiao, Y. Liu, R. Liu, M. Ashrafizadeh, João Conde*, C. Liu*, H. Huang* and C. Duan*
188. “DNA/RNA hybrid hairpin gold nanobeacons targeting miR‑31 reprogram invasion in lung cancer and remodel tumor histo‑architecture in vivo”
...
Diana P. Sousa and João Conde*
187. “Disulfide stress rewires collagen-CD44 signaling to shield cells from disulfidptosis by disrupting redox-stress complexes and restore bone integrity”
...
W. Jin, J. Chen, Y. Zhou, C. Zhong, João Conde*, Y. Zhang* and H. Peng*
186. “A reproducible workflow for macrophage membrane isolation and nanocore selection toward bioinspired nanoparticles targeting immunologically cold tumors”
...
Diana Peixoto, P. Diaz-Rodriguez, F. Veiga, A. Concheiro, A.C. Paiva-Santos, João Conde* and C. Alvarez-Lorenzo*
185. “Global, regional, and national burden of chronic respiratory diseases and the COVID-19 pandemic-driven estimates, 1990-2021: a Global Burden of Disease Study”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
184. “NFYB-lncRNA axis resets the tumor microenvironment to promote hepatocellular carcinoma aggressive progression by a positive feedback loop”
...
B. Zhou, Q. Tao, W. Wen, J. Tan, J. Xu, Y. Fang, J. Guan, X. Lin, J. He, M. Ashrafizadeh, Z. Wang*, João Conde* and F. Zheng*
183. “RBM30 drives immune escape via epigenetic activation of STAT1 in hepatocellular carcinoma”
...
H. Han, F. Wang, C. Duan, C. Liu, Y. Fu, Y. Wang, D. Zhao, Y. Tian, M. Ashrafizadeh, B. Li, João Conde*, Z. You* and Z. Gong*
182. “Targeting the USP46/BRPF3/E2F1 epigenetic axis with PG490 overrides Lenvatinib resistance in hepatocellular carcinoma”
...
Y. Zhang, F. Ma, L. Guo, Z. Wang, P. Jaydeepsinh, C. Qi, Y. Wang, C. Yang, H. Liu, D. Wang, X. Zhang, C. Jing, X. Wang, Z. Zhang, Y. Hou, M. Ashrafizade, João Conde*, Z. Ma*, W. Guo* and Z. Zhu*
181. “Multiregulatory supramolecular hydrogel nanocores reprogram cartilage homeostasis in osteoarthritis”
...
Y. Ma, Z. Wang, R. Zhang, C. Xu, João Conde*, Q. Zhai* and C. Chen*
180. “Global, regional, and national burden of breast cancer among females, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
179. “Mitochondrial flagella-like extensions (MitoFLARE) dysfunction triggers STING-mediated immune dysregulation in sepsis”
...
W. Hong, R. Ma, S. Long, R. Song, S. Ren, X. Ran, J. Wan, Y. Liu, X. Li, Q. Chen, D. Ma, Z. Zhang, H. Huang, M. Ashrafizadeh, João Conde*, L. Liu* and C. Duan*
178. “Global, regional, and national burden of healthcare-related adverse events, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
177. “Targeted delivery of selective BET inhibitors”
...
R. Traquete, E. Henderson, C. Tang, S. Picaud, A. Guerreiro, João Conde, T. Rodrigues, J.D. Seixas, P.M.S.D. Cal, T. Carvalho, R. Wilson, F. Corzana, A. Koehler, C. Goding, P. Filippakopoulos* and G.J.L. Bernardes*
176. “A multi-omics-driven diagnostic-prognostic model for precision immunotherapy of tumor-associated macrophages by reversing chemoresistance in colorectal cancer”
...
Y. Sun, K. Peng, Y. Li, D. Zheng, K. Yu, C. Xu, F. Zhao, Y. Zhou, J. Kuang, Z. Li*, João Conde*, C. Ying*, W. Wang* and W. Xiao*
175. “Microvesicle release drive cycles of mitophagy flux disruption and inflammatory amplification in sepsis-induced myocardial dysfunction”
...
R. Song, Y. Ma, J. Wan, S. Hao, B. Chen, Y. Liao, Y. Liao, Y. Xiao, X. Zhang, Z. Zhang, S. Ren, X. Tan, J. Tan, H. Huang, João Conde*, G. Sethi, L. Liu* and C. Duan*
174. “In vivo multimodal self-immolative prodrug nanomicelles modulate key intratumoral and metastatic genomic signalling pathways in pancreatic cancer”
...
João M.J.M. Ravasco, Jhenifer Oliveira, João Conniot, Bárbara B. Mendes, C. Leal, S.N. Fernandes, C.A.M. Afonso and João Conde*
173. “Global child and adolescent health in 204 countries and territories with special focus on the impacts of COVID-19 and conflict and terrorism, 1990−2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
172. “Global child and adolescent health scenarios across 204 countries and territories, 2022–2040: a deep learning forecasting analysis for the Global Burden of Disease Study 2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
171. “Cytoskeletal remodeling promotes tunneling nanotube formation and drives cardiac resident cell mitochondrial transfer in sepsis”
...
R. Song, C. Huang, Y. Ma, Z. Zhang, Y. Liu, B. Chen, X. Zhang, S. Hao, H. Huang, M. Ashrafizadeh, João Conde*, C. Duan*
170. “Succinate Dehydrogenase B (SDHB) Overexpression with Enzymatic Dysfunction Defines a Distinct Subtype of Undifferentiated Pleomorphic Sarcoma”
Cancer Research Communications (2025) - IF3.3
M. Esperança-Martins, H. Vasques, M. Sokolov Ravasqueira, (…), C. Melo-Alvim, Isabel Fernandes, D. López-Presa, M.M. Lemos, B.A. Van Tine, A.C.S. Bastos, S. Casimiro, N. Abecasis, L. Costa, E. Gonçalves, I.F. Duarte and S. Dias
169. “Structurally and functionally optimized silk fibroin-alginate-based biomimetic scaffolds reinforced with nanobioceramics for bone tissue engineering applications”
Journal of Nanobiotechnology (2025) - IF10.6
T-M.N. Nguyen, N-H.H. Le, M. Murugesan, G. Janarthanan, P. Manivasagan, E-S. Jang, Y. Li, V.H.G. Phana, S. Vijayavenkataraman*, João Conde* and T. Thambi*
164. “Ibero-American Consensus for the Management of Liver Metastases of Soft Tissue Sarcoma: Updated Review and Clinical Recommendations”
Cancers (2025) - IF4.4
R. Lopes-Brás, P. Muñoz, Eduardo Netto, J.Á. Fernández, M. Serradilla-Martín, P. Lozano, M. Esperança-Martins, G. Blanco-Fernández, J.A. González-López, F.C. Muñoz-Casares, Isabel Fernandes, J.M. Asencio-Pascual and H. Vasques
163. “One-pot synthesis of Mn/Fe bimetal-doped MOF as multifunctional nanocarriers for esophageal cancer targeted therapy”
Journal of Pharmaceutical Analysis (2025) - IF8.9
J. Ma, X. Zhang, X. Meng, Y. Dai, H. Wang, M. Ashrafizadeh, João Conde*, Z. Li*, E. Yao* and W. He*
161. “Transcriptomic-based classification identifies prognostic subtypes and therapeutic strategies in soft tissue sarcomas”
Cancers (2025) - IF4.4
M. Esperança-Martins, H. Vasques, M.S. Ravasqueira, M.M. Lemos, F, Fonseca, D. Coutinho, J.A. López, R.S.P. Huang, S. Dias, L. Gallego-Páez, L. Costa, N. Abecasis, E. Gonçalves and Isabel Fernandes
160. “Macrophage efferocytosis mediated by the TP63–RAC2 pathway promotes immunosuppressive remodeling in esophageal cancer”
Cell Reports Medicine (2025) - IF10.6
Y. Xi, Z. Xu, Z. Zhao, Y. Zhou, C. Yin, W. Jin, C. Lin, J. Kuang, B. Yu*, João Conde*, S. Liu* and W. Shen*
159. “Practical guidance on the detection of NTRK fusions in sarcomas: current status and diagnostic challenges”
Acta Médica Portuguesa (2025)
Isabel Fernandes, D. Macedo, E. Gouveia, A. Ferreira, J. Lima, D. Lopez, C. Melo-Alvim, A. Carvalho, P. Tavares, P. Rodrigues-Santos, P. Cardoso, M. Magalhães, P. Vieira, J. Brito, C. Mendes, J. Rodrigues, Eduardo Netto, V. Oliveira, C. Sousa, M.H. Abreu, F. Pina and H. Vasques
158. “Global, Regional and National Burden of Cardiovascular Diseases and Risk Factors in 204 countries and territories, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023”
Journal of the American College of Cardiology (2025) - IF22.3
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
157. “Accelerating discoveries in cancer nanomedicine using AI”
Cell Biomaterials (2025)
C. Guan, Bárbara B. Mendes, João Conniot, A.L. Dias, L. Hammad, T. Thambi, R. Langer*, T. Rodrigues*, João Conde* and C. de la Fuente-Nunez*
156. “A tumor microenvironment-responsive Zr-MOF nanosystem for co-delivering siHIF-1α and triptolide enhances photodynamic therapy in esophageal cancer by amplifying ROS generation and reversing hypoxia”
Materials Today Bio (2025) - IF10.2
W. Liu, C. Sun, Y. Dai, H. Wang, M. Ashrafizadeh, João Conde*, L. Yang* and W. Hea*
154. “Multiscale profiling of nanoscale metal-organic framework immune interactions”
Advanced Healthcare Materials (2025) - IF9.6
Y. Zhuang, Bárbara B. Mendes, D. Menon, Jhenifer Oliveira, X. Chen, F.D. Duman, João Conniot, S. Mercado, X. Liu, S. Zhang, J.J. Powell, João Conde*, R.E. Hewitt* and D. Fairen-Jimenez*
148. “Annexin A1 mRNA-loaded liposomes alleviate acute pancreatitis by suppressing STING pathway and promoting efferocytosis in macrophages”
Nature Nanotechnology (2025) - IF40.5
H. Fang, P. You, S. Lin, Y. Wu, J. Lin, Z. Hou, F. Liang, C. Chen, Z. Wang, L. Chen, S. Zhang, X. Chen, K. Zhao, F. Lu, M. Pan, Y. Zhou, C. Yin*, João Conde*, H. Huang* & Y. Pan*
147. “Bioengineered metastatic cancer nanovaccine with a TLR7/8 agonist for needle-free intranasal immunization”
Biomaterials (2025) - IF12.8
J.M. Jung, M.S. Lee, Y.K. Seo, J.E. Lee, S.Y. Lim, D.H. Kim, S.Y. Lyu, C. Park, B.D. Kim, J.H. Shin, J.H. Lee, P. Liu, J. Jung, João Conde, T. Thambi, J.H. Jeong and D.S. Lee
146. “Zn-DHM nanozymes enhance muscle regeneration through ROS scavenging and macrophage polarization in volumetric muscle loss revealed by single-cell profiling”
Advanced Functional Materials (2025) - IF18.5
X. Feng, Z. Luo, W. Zhang, R. Wan, Y. Chen, F. Li, Y. He, Z. Lin, J.H. Hui, Y. Li, João Conde*, S. Chen*, Z. Zhao*, X. Wang*
145. “Longan-inspired chitosan-pectin core-shell hydrogel beads for oral delivery of biodrugs to enhance osteoporosis therapy”
International Journal of Biological Macromolecules (2025) - IF7.7
V.H.G. Phan, B-P. T. Nguyen, N.Y. Nguyen, C-N. D. Tran, Q-N. D. Nguyen, C.H. Luu, P. Manivasagan, E-S Jang, D.C. Yang, D.U. Yang, Y. Li* João Conde * and T. Thambi*
144. “Age-associated reduction in ER-Mitochondrial contacts impairs mitochondrial lipid metabolism and autophagosome formation in the heart”
Cell Death & Differentiation (2025) - IF13.7
W. Hong, X. Zeng, R. Ma, Y. Tian, H. Miu, X. Ran, R. Song, Z. Luo, D. Ju, D. Ma, M. Ashrafizadeh, S.K. Bhutia, João Conde, G. Sethi*, H. Huang* and C. Duan*
139. “Rational design of Metal-Organic Frameworks for pancreatic cancer therapy: from machine learning screening to in vivo efficacy”
Advanced Materials (2025) - IF27.4 - Special issue on 30 Years of Reticular Materials
F. Melle, D. Menon, João Conniot, J. Ostolaza-Paraiso, X. Chen, S. Mercado, Jhenifer Oliveira, Bárbara B. Mendes, João Conde* and D. Fairen-Jimenez*
138. “Exploring the link between low germline mutational load and low breast cancer incidence: lessons from the Xavante Indians”
Translational Oncology (2025) - IF4.5
José Rueff*, João Conde* and Guilherme Castro*
† In the memory of our dear Professor José Rueff, an exceptional friend and mentor. Com amizade e carinho Professor
137. “Long-term cell-membrane coated ultrabright polymeric nano-dots for targeted cancer cell imaging and hydrophobic drug delivery”
Chemistry of Materials (2025) - IF7.2 - Polymer-Drug Conjugate Materials - Featured on COVER
Rajendra Prasad*, N. Gupta, A.S. Meena, V.G.S.S. Jyothi, A. Chan-dak and João Conde*
136. “Engineered biomimetic cisplatin-polyphenol nanocomplex for chemo-immunotherapy of glioblastoma by inducing pyroptosis”
Journal of Nanobiotechnology (2025) - IF10.6
X. Hao, Y. Tang, W. Xu, M. Wang, J. Liu, Y. Li, J. He, Y. Peng, P. Sun, D. Liao, X. Hu, T. Tang, M. Zhou, R. Han, J. Wang, João Conde*, D. Xiang* and J. Wu*
135. “Voices of Nanomedicine: blueprint guidelines for collaboration in addressing global unmet medical needs”
ACS Nano (2025) - IF15.8 - Featured on COVER
R. Prasad*, A. Ghosh, V. Patel, B. Peng, Bárbara B. Mendes, E.H.A. Win, L.G. Delogu, J.Y. Wong, K.J. Pische, J. Bellare, A. Bar-Shir, A.S. Thakor, W.J. Parak, Z.M. Bhujwalla, Y.S. Zhang, N. Kommineni, V. Rotello, W. Cai, T. Lammers, T.W. Odom, G. Padmanaban, D. Peer, J.F. Lovell, R. Srivastava*, R. Langer and João Conde*
130. “Forecasting the impacts of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050 - a systematic analysis for the Global Burden of Disease Study 2021”
The Lancet Public Health (2024) - IF25.4
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
129. “Triterpenoid saponin-based supramolecular host-guest injectable hydrogels inhibit the growth of melanoma via ROS-mediated apoptosis”
Materials Science and Engineering: R: Reports (2024) - IF31.6
R. Mathiyalagan, M. Murugesan, Z.M. Ramadhania, J. Nahar, P. Manivasagan, E-S. Jang, D.C. Yang,
João Conde* and T. Thambi*
123. “Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021”
The Lancet (2024) - Featured on COVER - IF168.9
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
122. “Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021”
The Lancet (2024) - Featured on COVER - IF168.9
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
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118. “Preclinical assessment of an antibiotic-free cationic surfactant-based hydrogel for sexually and perinatal transmitted infections”
Matter, Cell Press (2024) - IF20.0
R.D.A. Calado, Bárbara B. Mendes, João Conniot, João M.J.M. Ravasco, D. Sobral, C. Ferreira, R. Ferreira, J.C. Rodrigues, D. Santos, S. Duarte, L. Vieira, A.S. Inácio, H. Carrêlo, W.L.C. Vaz, J.P. Gomes, A. Nunes*, João Conde* and O.V. Vieira*
116. “Engineered nanomaterials for glioblastoma nanovaccination”
Nature Reviews Materials (2024) - Featured on COVER - IF86.2
F. Haamedat, Bárbara B. Mendes, João Conniot, L.D. Di Filippo, M. Chorilli, A. Schroeder, João Conde* and F. Sousa*
113. “Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic”
The Lancet (2024) - Featured on COVER - IF168.9
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium
109. “A Fluorinated BODIPY-Based Zirconium Metal-Organic Framework for in vivo Enhanced Photodynamic Therapy”
Journal American Chemical Society (2024) - IF16.4
X. Chen, Bárbara B. Mendes, Y. Zhuang, João Conniot, S.M. Argandona, F. Melle, Diana P. Sousa, D. Perl, A. Chivu, H. K. Patra, W. Shepard, João Conde* and D. Fairen-Jimenez*
104. “Intratumoural Delivery of mRNA Loaded on a Cationic Hyper-Branched Cyclodextrin-Based Polymer Induced an Anti-Tumour Immunological Response in Melanoma”
Cancers (2023) - IF6.6
F. Trotta, M. Mahmoudian, P. Zakeri-Milani, C. Cecone, K.J. Ishii, T. Hayashi, João Conde, A. Matencio and Y.K. Monfared
99. “Bioengineered exosome membrane camouflaged-abiotic nanocarriers: neurodegenerative diseases, tissue engineering and regenerative medicine”
Military Medical Research (2023) - IF34.9
D. Lopes, J. Lopes, M. Pereira-Silva, Diana Peixoto, N. Rabiee, F. Veiga, O. Moradi, Z.H. Guo, X.D. Wang, João Conde, P. Makvandi and A.C. Paiva-Santos
95. “Exosome Membrane-Coated Nanosystems: Exploring Biomedical Applications in Cancer Diagnosis and Therapy”
Matter, Cell Press (2023) - IF20.0
M. Shao, D. Lopes, J. Lopes, S. Yousefias, A. Macário-Soares, Diana Peixoto, I. Ferreira-Faria, F. Veiga, João Conde, Y. Huang, X. Chen, A.C. Paiva-Santos and P. Makvandi
92. “Magnetite and bismuth sulfide Janus heterostructures as radiosensitizers for in vivo enhanced radiotherapy in breast cancer”
Biomaterials Advances (2022) - IF8.4
H. Nosrati, M. Ghaffarlou, M. Salehiabar, N. Mousazadeh,F. Abhari, M. Barsbay, Y.N. Ertas, H. Rashidzadeh, A. Mohammadi, L. Nasehi, H. Rezaeejam, S. Davaran, A. Ramazani*, João Conde* and H.
Danafar*
87. “Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019”
The Lancet Gastroenterology & Hepatology (2022) - IF45.0
João Conde & GBD 2019 Colorectal Cancer Collaborators - Global Burden of Disease (GBD) Consortium
86. “PrimeView - Nanodelivery of nucleic acids”
Nature Reviews Methods Primers (2022) - IF50.1
Highlighted in the "Nobel Prize in Physiology or Medicine 2023" Collection
Bárbara B. Mendes, João Conniot, A. Avital, D. Yao, X. Jiang, X. Zhou, N. Sharf-Pauker, Y. Xiao, O. Adir, H. Liang*, J. Shi*, A. Schroeder* and João Conde*
86. “Nanodelivery of nucleic acids”
Nature Reviews Methods Primers (2022) - IF50.1
Highlighted in the "Nobel Prize in Physiology or Medicine 2023" Collection
Bárbara B. Mendes, João Conniot, A. Avital, D. Yao, X. Jiang, X. Zhou, N. Sharf-Pauker, Y. Xiao, O. Adir, H. Liang*, J. Shi*, A. Schroeder* and João Conde*
85. “Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019”
The Lancet Child & Adolescent Health (2022) - Featured on Cover - IF37.7
João Conde & GBD 2019 Collaborators - Global Burden of Disease (GBD) Consortium
83. “The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019”
The Lancet Oncology (2021) - Featured on COVER - IF54.4
João Conde & GBD 2019 Adolescent and Young Adult Cancer Collaborators - Global Burden of Disease (GBD) Consortium
82. “Prodrug polymeric nanoconjugates encapsulating gold nanoparticles for enhanced X-Ray radiation therapy in breast cancer”
Advanced Healthcare Materials (2021) - Rising Star Issue - Featured on COVER - IF11.1
H. Nosrati, F. Seidi, A. Hosseinmirzaei, N. Mousazadeh, A. Mohammadi, Mo. Ghaffarlou, H. Danafar, João Conde* and Ali Sharafi*
80. “Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019”
JAMA Oncology (2021) - IF33.0
João Conde & GBD 2019 Cancer Collaborators - Global Burden of Disease (GBD) Consortium
77. “Global, regional, and national progress toward Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019”
The Lancet (2021) Featured on COVER - IF202.7
João Conde & GBD 2019 Under-5 Mortality Collaborators - Global Burden of Disease (GBD) Consortium
75. “Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression”
ACS Central Science (2021) Featured on COVER - IF18.7
João Conde, R.A. Pumroy, C. Baker, T. Rodrigues, (...), F. Corzana, V.A. Morais, C.C. Faria, T. Carvalho, P. Filippakopoulos, B. Snijder, N.L. Barbosa-Morais, V.Y. Moiseenkova-Bell, G.J.L. Bernardes
73. “Ultrahigh penetration and retention of graphene quantum dot mesoporous silica nanohybrids for image guided tumor regression”
ACS Applied Bio Materials (2021) Featured on COVER - IF3.3
R. Prasad*, N.K. Jain, A.S. Yadav, M. Jadhav, N.N.V. Radharani, M. Gorain, G.C. Kundu, João Conde*, R. Srivastava*
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64. “Platinum-triggered Bond-cleavage of Pentynoyl amide and N-propargyl handles for Drug-Activation”
Journal American Chemical Society (2020) Featured on COVER - IF16.4
B.L. Oliveira, B.J. Stenton, Unnikrishnan V.B., C.R. Almeida, João Conde, M. Negrão, F.S.S. Schneider, C. Cordeiro, M.G. Ferreira, G.F. Caramori, J.B Domingos, R. Fior and G.J.L. Bernardes
63. “Stepwise Assembly of Multimode Liposomal Nanotheranostic Agent for Targeted In Vivo Bioimaging and NIR Light Mediated Cancer Therapy”
Communications Biology (2020) - IF6.5
R. Prasad, N.K. Jain, A.S. Yadav, D.S. Chauhan, J. Devrukhkar, M.K. Kumawat, S. Shinde, M. Gorain, A.S. Thakor, G.C. Kundu, João Conde*, R. Srivastava*
60. “Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression”
Cell Sneak Peek (2019) - IF41.6
C. Baker*, T. Rodrigues*, R.A. Pumroy*, João Conde*, D. Picard, M.C. Marques, B.P. de Almeida, A. Samanta, F. Sieglitz, M. Langini, M. Remke, R. Roque, F. Corzana, C.C. Faria, T. Carvalho, N.L. Barbosa-Morais, V.Y. Moiseenkova-Bell, G.J.L. Bernardes
58. “Oral pH sensitive GNS@ab Nanoprobes for targeted therapy of Helicobacter Pylori without disturbance gut microbiome”
Nanomedicine: Nanotechnology, Biology and Medicine (2019) - IF6.5
X. Zhi, Y. Liu, L. Lin, M. Yang, L. Zhang, L. Zhang, Y. Liu, G. Alfranca, L. Ma, Q. Zhang, H. Fu, João Conde, X. Di, J. Ni, J. Song, D. Cui
57. “Gastric parietal cell and Intestinal goblet cell secretion: a novel cell-mediated in vivo nanoparticle clearance pathway enhanced with diarrhea via Chinese Herbs”
Nanoscale Research Letters (2019) - IF5.4
Y. Liu, K. Liu, M. Yang, Y. Han, Q. Zhang, João Conde, Y. Yang, Y. Han, G. Alfranca, Y. Wang, J. Song, Y. Zhang, J. Ni, J.M. de la Fuente, D. Cui
33. “Significance of the balance between intracellular glutathione and polyethylene glycol for successful release of small interfering RNA from gold nanoparticles”
Nano Research (2015) - IF10.3
M. McCully, Y. Hernandez, João Conde, P.V. Baptista, J.M. de la Fuente, A. Hursthouse, D. Stirling and C.C.Berry
30. “Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells”
Advanced Functional Materials (2015). Featured on COVER - IF19.9
João Conde*, C. Bao, Y. Tan, D. Cui, E.R. Edelman, H.S. Azevedo, H.J. Byrne, N. Artzi and F. Tian*
9. “Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair”
Environment International (2012) - IF13.3
J. García-Lestón, J. Roma-Torres, M. Vilares, R.Pinto, J. Prista, J.P. Teixeira, O. Mayan, João Conde, M. Pingarilho, J.F. Gaspar, E. Pásaro, J. Méndez and B. Laffon
