
PUBLICATIONs

225. “Pan-cancer analysis of fibroblasts and macrophages defines a prognostic stromal-immune axis in breast cancer”
...
...

224. “In situ-forming hydrogel for spatiotemporally controlled delivery of homologous cancer cell membrane-coated micelles toward metastatic pancreatic cancer therapy”
...
Diana Peixoto, Catarina F. Martins, P. Diaz-Rodriguez, F. Veiga, A. Concheiro, A.C. Paiva-Santos, C. Alvarez-Lorenzo and João Conde

223. “CD52 is a clinically relevant regulator of tumor-immune interactions in lymph node metastasis”
...
Y. Xi, L. Li, C. Xu, F. Zhao, F. Ye, M. Yuan, C. Ye, L. Jiang, Y. Huang, J. Zhang, W. Shen, J. Kuang, A.K. Barui, M. Shanmuganathan, Y. Zhou*, H. Chen*, João Conde* and B. Yu*

222. “3D bioprinted endometriosis model with fibrin bioinks for nanoparticle-Photo-Thermal Therapy evaluation”
...
Cristina Volpini, G. Guagliano, N. Bloise, Barbara B. Mendes, F.B. Vangosa, P. Petrini, B. Gardella, S. Ferrero, João Conde, P. Minzioni and L. Visai*

221. “Imaging-guided NIR-II theranostic nanoprobes disable m6A reader-stabilized resistance mRNAs in pancreatic cancer”
...
J. Zhu, X. Wang, Y. Xu, S. Fang, K. Zhao, Z. Yu, X. Xu, J. Zhang, M. Zhang, B. Gan, J. Lu, R. Zhou, Y. Chen, J. Sun, João Conde* and S. Zheng*

220. “Global, regional and national burden of cervical cancer and associated risk factors from 1990 to 2023 and forecasts to 2050: A systematic analysis for the Global Burden of Disease Study 2023”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

219. “Machine learning prediction of patient-relevant toxicity to liposomal formulations via pre-dose metabolomics”
...
M. Zhao, , Y. Wang, Y. Xiao, G. Hu, Y. Zou, J. Li, L. Zhao, X. Ye, H. Liu, João Conde*, Y. Zhao* C. Yin* and H. Meng*

218. “IL-10-accelerated cancer immunotherapy: Molecular circuitry, TME dynamics and translational implications”
...
Y. Tian, S. Fu, Z. Liu, X. Wang, Q. Wang, E. Shen, Q. Zhou, M. Ashrafizadeh, João Conde*, S. Wang* and Q. Yin*

217. “Preclinical validation of a therapeutic nose-to-brain delivery for gliomas using a mucoadhesive thermoresponsive lipid nanoparticle hydrogel”
...
Leonardo D. Di Filippo, J.L. Duarte, Bárbara B. Mendes, Jhenifer Oliveira, Catarina F. Martins, Mariana F. Pereira, G.A. de Paula, T.C. Ribeiro, F.F. Haddad, I.D. Figueiredo, R.M. Sábio, B.S. Rosa, G. Morais-Silva, M. Thiele, C.C. Crestani, R.L. Nunes-de-Souza, E. Sasso-Cerri, M. Chorilli* and João Conde*

216. “DNA demethylation rewires oncogenic transcription to tumor microenvironment immune exhaustion in lung adenocarcinoma”
...
Y. Xi, S. Liu, T. Wang, W. Zuo, D. Ling, F. Zhao, Y. Zhou, J. Kuang, W. Shen, X. Liu*, R. Rajandram*, S. Krishnasamy*, João Conde* and B. Yu*

215. “Rinse-triggered thermoresponsive polymer coatings for on-demand biofilm shedding and tissue integration on dental implants in multiple in vivo mammalian and human models”
...
S. Ye, M. Zhang, Z. Wu, K. Zou, Q. Yu, R. Zhong, W. Huang, T. Yang*, João Conde*, W. Li* and L. Wang*

214. “Materials-guided gene-ionizable lipid nanoparticles to reverse iron-associated immune resistance in renal cancer”
...
X. Jin, Y. Hong, C. Yin, W. Guo, Y. Wang, R. Zeng, R. Liu, Z. Ding, X. Liu, S. Ren, Q. Liang, Y. Wang, X. Zhang, João Conde*, Y. Li*, X. Ma* and L. Gu*

213. “Measuring the composition and availability of human resources for health by sex in 204 countries, 1990–2023, and workforce gaps for universal health coverage”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

212. “Injectable heterojunction nanozyme-doped thermoresponsive hydrogel for synergistic ROS scavenging and microenvironment remodeling in osteoarthritis cartilage regeneration”
...
K. Zhang, M. Jiang, G. Lai, M. Li, C. Lei, Q. Liao, Z. Wang, Y. Tian, T. Wang, S. Wu, C. Yang, Hu. Zhao, J. He, L. Lu, J. Meng, Z. Lin, X. Gan, Y. Liu, Z. Yuan, W.S. Toh, J.HP. Hui, X. Zheng, Z. Wang, M. Ashrafizadeh, João Conde*, Z. Bo*, Z. Wang*, S. Lu* and R. Wei*

211. “Patient-grounded proteostatic-metabolic tripartite signaling nanocircuit dismantles in vivo tumor-stroma lipid symbiosis in pancreatic cancer”
...
J. Zhu, C. Huang, X. Wang, J. Zhang, S. Fang, K. Zhao, Z. Yu, Y. Xu, M. Zhang, B. Gan, J. Lu, R. Zhou, Y. Chen, B. Zhang, X. Ren, J. Sun, João Conde* and S. Zheng*

210. “Intrinsically targeted endothelial EVs nanoplatform synergizes hydrogen sulfide for multi-target vascular repair”
...
B. Gao, J. Sun, P. Wei, Y. Zhang, Y. Tian, Y. Lin, M. Ashrafizadeh, D. Kang*, João Conde* and X. Niu*

209. “Global trends in maternal, neonatal infections and sepsis, 1990–2021: a systematic analysis”
...
X. Tan, Y. Feng, J. Hu, K. Sun, Y. Fu, Z. Zhang, M. Ashrafizadeh, João Conde*, A. Zhang*, D. Ma* and C. Duan*

208. “Nanoparticle-mediated photothermal therapy for Acne vulgaris: recent clinical advances and AI integration”
...
P. Manivasagan, A. Joe, H-W. Han, T. Thambi, Y.J. Jeon, Y-R. Lim, J. Choi, João Conde* and E-S. Jang*

207. “ZDHHC16-mediated S-palmitoylation of WDR4 enhances m7G modification and EGFR translation to facilitate liver cancer progression and lenvatinib resistance”
...
Y. Chen, Q. Dai, H. Wang, J. Zhang, B. Li, S. Li, Y. Tian, M. Ashrafizadeh, João Conde*, Z. You* and L. Jiang*

206. “Wearable near-infrared LED photothermal microneedle patches reduce periorbital wrinkles in a randomized pilot clinical trial”
...
Hyo-Won Han, D-H. Lee, A. Joe, Y.J. Jeon, Y-R. Lim, J. Choi, S.B. Lee, B-H. Bin, T. Thambi, João Conde*, P. Manivasagan* and E-S. Jang*

205. “A self-replicating mRNA vaccine targeting p53 mutants elicits potent anti-tumor immunity against pancreatic cancer”
...
C. Chen, C. Huang, Y. Wu, Z. Hou, F. Liang, J. Lin, P. You, S. Lin, Y. Zhang, H. Zhang, H. Huang*, João Conde*, M. Pan* and Y. Pan*

204. “Clinically relevant glycolytic reprogramming by ALDOA fuels immunosuppressive macrophages and pancreatic tumor growth”
...
J. Lin, M. Tian, Z. Hou, C. Chen, Y. Wu, F. Liang, L. Wu, P. You, Y. Mao, Z. Zhao, J. Kuang, X. Meng, Y. Zhou, W. Jia, H. Huang*, João Conde*, P. Zhao* and Y. Pan*

203. “BRPF1 is an epigenetic checkpoint for β-catenin and NF-κB to drive immune suppression”
...
Y. Hou, F. Ma, F. Meng, Z. Yang, Z. Wang, Y. Tian, ... , G. Sethi, D. Yin, R. Song, A.R. Aref, C. Nicot, M. Ashrafizadeh, João Conde*, J. Wang*, C. Zhang* and L. Liu*

202. “Global, Regional and National Distributions and Temporal Trends of Lung Cancer Burden Attributable to Residential Radon, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

201. “Spatiotemporal Distributions and Regional Disparities of Chronic Myeloid Leukemia in 953 Global to Subnational Locations, 1980–2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

200. “Dual-module nanoplatform synchronizes mitophagy and mitochondrial replenishment to reverse septic cardiac dysfunction”
...
R. Song, Y. Ma, K. Sun, F. Liang, Q. Zeng, Y. Liao, Y. Xiao, Y. Liao, X. Tan, J. Tan, X. Ran, M. Ashrafizadeh, G. Sethi, João Conde* and C. Duan*

199. “Agentic AI systems for the next generation of Brain-Computer Interfaces”
...
C. Liu, X. Zhou, J. Mao, Y. Ding, Q. Li, Z. Sun, J. Fang, G. Zhang, H. Wu, Y. Jin, Z. Jia, Y. Liu, H. Li, M. Qiu, D. Mandic, W. Jin, S. Luo, H. Liu, L. Deng, K. Wang, João Conde and Q. Wen

198. “TRIM14 is a key factor in the type I IFN and mitochondrial axis”
...
B. Huang, H. Li, C. Jin, W. Jin, Z. Chen, Z. Tai, Q. Jiang, Y. Liu, D. Gao, L. Yang, Y-L. Lau, X. Wang, João Conde*, J. Li* and F. Yang*

197. “Deep learning forecasts reveal widening global inequalities in global-to-local childhood and adolescent cancer burden”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

196. “Integrative multi-omics analysis reveals gut microbiome-bile acid axis dysregulation driving NAFLD progression and identifies Faecalibacterium prausnitzii as a therapeutic modulator”
...
S. Zhu, M. Zou, Q. Wu, Z. Huang, Y. Zou, T. Tan, Y. You*, H. Luo*, João Conde* and X. Dong*

195. “A predictive rheological framework to define printability of thermo-sensitive bioinks using non-temperature-controlled bioprinters”
...
I. Anjos, T. Vieira, T. Aktar, J.C. Silva, Barbara B. Mendes, João Conde, L.F Bolaños, S. Fernandes, C. Leal, J.P. Borges and D. Limón*

194. “Dexmedetomidine restores mitophagy and limits reperfusion injury to protect cold-stored organs”
...
X. Tan, Y. Liao, Y. Liu, G. Chen, G. Peng, B. Chen, S. Ren, Y. Liao, Y. Xiao, Y. Liu, R. Liu, M. Ashrafizadeh, João Conde*, C. Liu*, H. Huang* and C. Duan*

193. “COL4A2 expressing huMSCs reprogrammed CD44 function conteracting osteoblastic disulfidptosis for stem cell based therapeutics of osteonecrosis of the femoral head”
...
W. Jin, Y. Zhong, Y. Zhou, João Conde*, H. Peng*, Y. Zhang* and M. Gao*

192. “Targeting the USP46/BRPF3/E2F1 epigenetic axis with PG490 overrides Lenvatinib resistance in hepatocellular carcinoma”
...
Y. Zhang, F. Ma, L. Guo, Z. Wang, P. Jaydeepsinh, C. Qi, Y. Wang, C. Yang, H. Liu, D. Wang, X. Zhang, C. Jing, X. Wang, Z. Zhang, Y. Hou, M. Ashrafizade, João Conde*, Z. Ma*, W. Guo* and Z. Zhu*

191. “Multiregulatory supramolecular hydrogel nanocores reprogram cartilage homeostasis in osteoarthritis”
...
Y. Ma, Z. Wang, R. Zhang, C. Xu, João Conde*, Q. Zhai* and C. Chen*

190. “Global, regional, and national burden of healthcare-related adverse events, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

189. “Targeted delivery of selective BET inhibitors”
...
R. Traquete, E. Henderson, C. Tang, S. Picaud, A. Guerreiro, João Conde, T. Rodrigues, J.D. Seixas, P.M.S.D. Cal, T. Carvalho, R. Wilson, F. Corzana, A. Koehler, C. Goding, P. Filippakopoulos* and G.J.L. Bernardes*

188. “A multi-omics-driven diagnostic-prognostic model for precision immunotherapy of tumor-associated macrophages by reversing chemoresistance in colorectal cancer”
...
Y. Sun, K. Peng, Y. Li, D. Zheng, K. Yu, C. Xu, F. Zhao, Y. Zhou, J. Kuang, Z. Li*, João Conde*, C. Ying*, W. Wang* and W. Xiao*

187. “Mitochondrial Flagella-like Extensions (MitoFLARE) dysfunction triggers STING-mediated immune dysregulation in sepsis”
...
W. Hong, R. Ma, S. Long, R. Song, S. Ren, X. Ran, J. Wan, Y. Liu, X. Li, Q. Chen, D. Ma, Z. Zhang, H. Huang, M. Ashrafizadeh, João Conde*, L. Liu* and C. Duan*

186. “Smart multifunctional hydrogels with shape memory, conductivity, self-healing and adhesive properties for biomedical applications”
...
H. Huong, C.H. Luu, V.H. Giang Phan, G. Janarthanan, N-T. Huynh, H.T. Nguyen, N-Y. N. Ha, H.T. Ta, S. Vijayavenkataraman*, João Conde* and T. Thambi*

185. “SIRT3 deficiency impairs mitochondrial bioenergetics via hyperacetylation of TCA cycle enzymes in chronic heart failure”
...
Y. Liao, X. Tan, G. Peng, Y. Ren, R. Liu, H. Liao, Z. Luo, Z. Cao, Y. Wu, M. Ashrafizadeh, João Conde*, C. Duan*, J. Hu* and R. Ma*

184. “Global child and adolescent health in 204 countries and territories with special focus on the impacts of COVID-19 and conflict and terrorism, 1990−2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

183. “Global child and adolescent health scenarios across 204 countries and territories, 2022–2040: a deep learning forecasting analysis for the Global Burden of Disease Study 2021”
...
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

182. “One-pot synthesis of Mn/Fe bimetal-doped MOF as multifunctional nanocarriers for esophageal cancer targeted therapy”
...
J. Ma, X. Zhang, X. Meng, Y. Dai, H. Wang, M. Ashrafizadeh, João Conde*, Z. Li*, E. Yao* and W. He*

181. “In vivo multimodal self-immolative prodrug nanomicelles modulate key intratumoral and metastatic genomic signalling pathways in pancreatic cancer”
...
João M.J.M. Ravasco, Jhenifer Oliveira, João Conniot, Bárbara B. Mendes, C. Leal, S.N. Fernandes, C.A.M. Afonso and João Conde*

180. “Mapping Burdens and Inequalities of Polycystic Ovary Syndrome in Young Female across 953 Locations 1990 to 2040 with Deep Learning Forecasts”
iScience (2026) - IF4.1 (just accepted)
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

179. “Microvesicle release drive cycles of mitophagy flux disruption and inflammatory amplification in sepsis-induced myocardial dysfunction”
PNAS (2026) - IF10.6 (just accepted)
R. Song, Y. Ma, J. Wan, S. Hao, B. Chen, Y. Liao, Y. Liao, Y. Xiao, X. Zhang, Z. Zhang, S. Ren, X. Tan, J. Tan, H. Huang, João Conde*, G. Sethi, L. Liu* and C. Duan*

178. “Macrophage membrane-cloaked, ROS-triggered quercetin nanocarriers target ovarian lesions to treat polycystic ovary syndrome”
Advanced Healthcare Materials (2026) - IF9.6 (just accepted)
W. Li, Y. Guan, N. Song, F. Zhang, Z. Deng, T. Yin, Y. Yang*, João Conde*, W. Jin* and Z. Yin*

177. “Cytoskeletal remodeling promotes tunneling nanotube formation and drives cardiac resident cell mitochondrial transfer in sepsis”
Science Advances (2026) - IF12.5 (just accepted)
R. Song, C. Huang, Y. Ma, Z. Zhang, Y. Liu, B. Chen, X. Zhang, S. Hao, H. Huang, M. Ashrafizadeh, João Conde*, C. Duan*

176. “DNA/RNA hybrid hairpin gold nanobeacons targeting miR‑31 reprogram invasion in lung cancer and remodel tumor histo‑architecture in vivo”
ACS Materials Au (2026) - IF6.5 (just accepted)
Diana P. Sousa, Jhenifer Oliveira, Catarina F. Martins and João Conde*

174. “Global, regional, and national burden of breast cancer among females, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023”
The Lancet Oncology (2026) - IF35.9 (just accepted)
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

173. “NFYB-lncRNA axis resets the tumor microenvironment to promote HCC aggressive progression by a positive feedback loop”
Acta Pharmaceutica Sinica B (2026) - IF14.6 (just accepted)
B. Zhou, Q. Tao, W. Wen, J. Tan, J. Xu, Y. Fang, J. Guan, X. Lin, J. He, M. Ashrafizadeh, Z. Wang*, João Conde* and F. Zheng*

170. “Global to local burdens, inequalities, and achievable frontiers of child and adolescent malignant neoplasm of bone and articular cartilage across 953 countries and sublocations, 1980-2040, with deep learning-based forecasts”
Journal of Orthopaedic Translation (2026) - IF7.8
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

169. “Succinate Dehydrogenase B (SDHB) Overexpression with Enzymatic Dysfunction Defines a Distinct Subtype of Undifferentiated Pleomorphic Sarcoma”
Cancer Research Communications (2025) - IF3.3
M. Esperança-Martins, H. Vasques, M. Sokolov Ravasqueira, (…), C. Melo-Alvim, Isabel Fernandes, D. López-Presa, M.M. Lemos, B.A. Van Tine, A.C.S. Bastos, S. Casimiro, N. Abecasis, L. Costa, E. Gonçalves, I.F. Duarte and S. Dias

168. “Structurally and functionally optimized silk fibroin-alginate-based biomimetic scaffolds reinforced with nanobioceramics for bone tissue engineering applications”
Journal of Nanobiotechnology (2025) - IF10.6
T-M.N. Nguyen, N-H.H. Le, M. Murugesan, G. Janarthanan, P. Manivasagan, E-S. Jang, Y. Li, V.H.G. Phana, S. Vijayavenkataraman*, João Conde* and T. Thambi*

166. “Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023”
The Lancet (2025) - IF98.4 - Featured on COVER
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

163. “Ibero-American Consensus for the Management of Liver Metastases of Soft Tissue Sarcoma: Updated Review and Clinical Recommendations”
Cancers (2025) - IF4.4
R. Lopes-Brás, P. Muñoz, Eduardo Netto, J.Á. Fernández, M. Serradilla-Martín, P. Lozano, M. Esperança-Martins, G. Blanco-Fernández, J.A. González-López, F.C. Muñoz-Casares, Isabel Fernandes, J.M. Asencio-Pascual and H. Vasques

161. “Transcriptomic-based classification identifies prognostic subtypes and therapeutic strategies in soft tissue sarcomas”
Cancers (2025) - IF4.4
M. Esperança-Martins, H. Vasques, M.S. Ravasqueira, M.M. Lemos, F, Fonseca, D. Coutinho, J.A. López, R.S.P. Huang, S. Dias, L. Gallego-Páez, L. Costa, N. Abecasis, E. Gonçalves and Isabel Fernandes

159. “Practical guidance on the detection of NTRK fusions in sarcomas: current status and diagnostic challenges”
Acta Médica Portuguesa (2025)
Isabel Fernandes, D. Macedo, E. Gouveia, A. Ferreira, J. Lima, D. Lopez, C. Melo-Alvim, A. Carvalho, P. Tavares, P. Rodrigues-Santos, P. Cardoso, M. Magalhães, P. Vieira, J. Brito, C. Mendes, J. Rodrigues, Eduardo Netto, V. Oliveira, C. Sousa, M.H. Abreu, F. Pina and H. Vasques

158. “Global, Regional and National Burden of Cardiovascular Diseases and Risk Factors in 204 countries and territories, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023”
Journal of the American College of Cardiology (2025) - IF22.3
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

156. “A tumor microenvironment-responsive Zr-MOF nanosystem for co-delivering siHIF-1α and triptolide enhances photodynamic therapy in esophageal cancer by amplifying ROS generation and reversing hypoxia”
Materials Today Bio (2025) - IF10.2
W. Liu, C. Sun, Y. Dai, H. Wang, M. Ashrafizadeh, João Conde*, L. Yang* and W. Hea*

154. “Multiscale profiling of nanoscale metal-organic framework immune interactions”
Advanced Healthcare Materials (2025) - IF9.6
Y. Zhuang, Bárbara B. Mendes, D. Menon, Jhenifer Oliveira, X. Chen, F.D. Duman, João Conniot, S. Mercado, X. Liu, S. Zhang, J.J. Powell, João Conde*, R.E. Hewitt* and D. Fairen-Jimenez*

148. “Annexin A1 mRNA-loaded liposomes alleviate acute pancreatitis by suppressing STING pathway and promoting efferocytosis in macrophages”
Nature Nanotechnology (2025) - IF40.5
H. Fang, P. You, S. Lin, Y. Wu, J. Lin, Z. Hou, F. Liang, C. Chen, Z. Wang, L. Chen, S. Zhang, X. Chen, K. Zhao, F. Lu, M. Pan, Y. Zhou, C. Yin*, João Conde*, H. Huang* & Y. Pan*

147. “Bioengineered metastatic cancer nanovaccine with a TLR7/8 agonist for needle-free intranasal immunization”
Biomaterials (2025) - IF12.8
J.M. Jung, M.S. Lee, Y.K. Seo, J.E. Lee, S.Y. Lim, D.H. Kim, S.Y. Lyu, C. Park, B.D. Kim, J.H. Shin, J.H. Lee, P. Liu, J. Jung, João Conde, T. Thambi, J.H. Jeong and D.S. Lee

146. “Zn-DHM nanozymes enhance muscle regeneration through ROS scavenging and macrophage polarization in volumetric muscle loss revealed by single-cell profiling”
Advanced Functional Materials (2025) - IF18.5
X. Feng, Z. Luo, W. Zhang, R. Wan, Y. Chen, F. Li, Y. He, Z. Lin, J.H. Hui, Y. Li, João Conde*, S. Chen*, Z. Zhao*, X. Wang*

145. “Longan-inspired chitosan-pectin core-shell hydrogel beads for oral delivery of biodrugs to enhance osteoporosis therapy”
International Journal of Biological Macromolecules (2025) - IF7.7
V.H.G. Phan, B-P. T. Nguyen, N.Y. Nguyen, C-N. D. Tran, Q-N. D. Nguyen, C.H. Luu, P. Manivasagan, E-S Jang, D.C. Yang, D.U. Yang, Y. Li* João Conde * and T. Thambi*

144. “Age-associated reduction in ER-Mitochondrial contacts impairs mitochondrial lipid metabolism and autophagosome formation in the heart”
Cell Death & Differentiation (2025) - IF13.7
W. Hong, X. Zeng, R. Ma, Y. Tian, H. Miu, X. Ran, R. Song, Z. Luo, D. Ju, D. Ma, M. Ashrafizadeh, S.K. Bhutia, João Conde, G. Sethi*, H. Huang* and C. Duan*

139. “Rational design of Metal-Organic Frameworks for pancreatic cancer therapy: from machine learning screening to in vivo efficacy”
Advanced Materials (2025) - IF27.4 - Special issue 30 Years Reticular Materials - Featured on COVER
F. Melle, D. Menon, João Conniot, J. Ostolaza-Paraiso, X. Chen, S. Mercado, Jhenifer Oliveira, Bárbara B. Mendes, João Conde* and D. Fairen-Jimenez*

138. “Exploring the link between low germline mutational load and low breast cancer incidence: lessons from the Xavante Indians”
Translational Oncology (2025) - IF4.5
José Rueff*, João Conde* and Guilherme Castro*
† In the memory of our dear Professor José Rueff, an exceptional friend and mentor. Com amizade e carinho Professor

137. “Long-term cell-membrane coated ultrabright polymeric nano-dots for targeted cancer cell imaging and hydrophobic drug delivery”
Chemistry of Materials (2025) - IF7.2 - Polymer-Drug Conjugate Materials - Featured on COVER
Rajendra Prasad*, N. Gupta, A.S. Meena, V.G.S.S. Jyothi, A. Chan-dak and João Conde*

136. “Engineered biomimetic cisplatin-polyphenol nanocomplex for chemo-immunotherapy of glioblastoma by inducing pyroptosis”
Journal of Nanobiotechnology (2025) - IF10.6
X. Hao, Y. Tang, W. Xu, M. Wang, J. Liu, Y. Li, J. He, Y. Peng, P. Sun, D. Liao, X. Hu, T. Tang, M. Zhou, R. Han, J. Wang, João Conde*, D. Xiang* and J. Wu*

135. “Voices of Nanomedicine: blueprint guidelines for collaboration in addressing global unmet medical needs”
ACS Nano (2025) - IF15.8 - Featured on COVER
R. Prasad*, A. Ghosh, V. Patel, B. Peng, Bárbara B. Mendes, E.H.A. Win, L.G. Delogu, J.Y. Wong, K.J. Pische, J. Bellare, A. Bar-Shir, A.S. Thakor, W.J. Parak, Z.M. Bhujwalla, Y.S. Zhang, N. Kommineni, V. Rotello, W. Cai, T. Lammers, T.W. Odom, G. Padmanaban, D. Peer, J.F. Lovell, R. Srivastava*, R. Langer and João Conde*

130. “Forecasting the impacts of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050 - a systematic analysis for the Global Burden of Disease Study 2021”
The Lancet Public Health (2024) - IF25.4
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

129. “Triterpenoid saponin-based supramolecular host-guest injectable hydrogels inhibit the growth of melanoma via ROS-mediated apoptosis”
Materials Science and Engineering: R: Reports (2024) - IF31.6
R. Mathiyalagan, M. Murugesan, Z.M. Ramadhania, J. Nahar, P. Manivasagan, E-S. Jang, D.C. Yang,
João Conde* and T. Thambi*

123. “Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021”
The Lancet (2024) - Featured on COVER - IF168.9
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

122. “Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021”
The Lancet (2024) - Featured on COVER - IF168.9
João Conde & GBD Collaborators - Global Burden of Disease (GBD) Consortium

118. “Preclinical assessment of an antibiotic-free cationic surfactant-based hydrogel for sexually and perinatal transmitted infections”
Matter, Cell Press (2024) - IF20.0
R.D.A. Calado, Bárbara B. Mendes, João Conniot, João M.J.M. Ravasco, D. Sobral, C. Ferreira, R. Ferreira, J.C. Rodrigues, D. Santos, S. Duarte, L. Vieira, A.S. Inácio, H. Carrêlo, W.L.C. Vaz, J.P. Gomes, A. Nunes*, João Conde* and O.V. Vieira*

116. “Engineered nanomaterials for glioblastoma nanovaccination”
Nature Reviews Materials (2024) - Featured on COVER - IF86.2
F. Haamedat, Bárbara B. Mendes, João Conniot, L.D. Di Filippo, M. Chorilli, A. Schroeder, João Conde* and F. Sousa*

113. “Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic”
The Lancet (2024) - Featured on COVER - IF168.9
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109. “A Fluorinated BODIPY-Based Zirconium Metal-Organic Framework for in vivo Enhanced Photodynamic Therapy”
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